Hepatitis C
Description
Hepatitis C virus (HCV) causes a swelling of the liver and stops it from
working correctly. It can be transmitted by sharing drug needles or by
being pricked with an infected needle, being born to a mother who has
it, having multiple sex partners, or in rare cases, through a blood
transfusion or a tattoo administered with an unsterilized needle.
As with hepatitis B, if left untreated, HCV can become chronic, causing serious liver disease. At least 75% of individuals with HCV develop the chronic variety. Some four million individuals in the U.S. have the antibodies to HCV and have been infected with it at some point. As many as half of them do not know that they have the infection. HCV is infectious and there is not vaccination against it.
Symptoms
Of those infected, many — estimates are as high as 80% —
don’t show symptoms. For those who do, these symptoms may not
appear for a decade or more. And when they do, they can be as mild as
the flu. But once these symptoms do appear, damage may be very serious.
Symptoms for the minority of individuals, develop
5-12 weeks after exposure and can include:
• fatigue/sore muscles
• fever
• loss of appetite
• stomach pain
• nausea
• vomiting
• diarrhea
• dark yellow urine
• light-colored stool
Test
Individuals often find out they have HCV by accident during a routine
blood test that detects antibodies to the viruses. A blood test for HCV
specifically will detect how serious the infection is and whether an
individual has been exposed to other hepatitis viruses. Additional tests
can be done to determine the state of the liver. In some cases a liver
biopsy can be done via a needle to check for signs of HCV as well as for
damage to the liver.
Outcomes
A combination of drugs, possibly including Interferon with Ribavirin,
can be administered. The decision to proceed with this form of treatment
would be likely made by a gastroenterologist or liver specialist, based
on results of lab tests to assess liver function in combination with
patient history.
To abate symptoms, plenty of rest and fluids are recommended along with avoiding alcohol and Tylenol, which could both harm the liver. Most treatments can be taken at home, but if more serious signs like dehydration appear, hospitalization is recommended.
In some cases, IV fluids can aid in recovery from the symptoms, and medicines for nausea and vomiting can be prescribed. For those who have had HCV for many years and have progressed to end-stage liver disease, there is the potential for a liver transplant.
-
Resources
- www.gastro.org/wmspage.cfm?parm1=2
- www.liverfoundation.org
- www.cdc.gov/ncidod/diseases/hepatitis/index.htm
- www.hepfi.org